Journal: Drug Invention Today

Article Id: JPRS-Pcol-00004431
Title: Effects of Vitamin E supplementation on glycemic control and cardiovascular risk in patients with type II diabetes mellitus
Category: Pharmacology
Section: Research Article
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    Objectives: The main objectives are to understand the outcomes of Vitamin E supplementation for Type II diabetes mellitus patients receiving a standard oral hypoglycemic agent. There is a need to study the impact of these antioxidant vitamins in these metabolic disorders. Materials and Methods: A randomized parallel allocated study has been carried out to study the impact of Vitamin E supplementation with one group receiving metformin 500 mg BD + Vitamin E 400 IU OD and Group B receiving metformin 500 mg BD and placebo once daily. Their effects on fasting blood glucose, glycated hemoglobin, troponin T levels, lipid profile, etc. Results: A total of 80 patients were grouped into two groups. It was found that the group which received Vitamin E had a slight reduction in fasting blood sugar levels but not a significant difference (P = 0.0568). A significant reduction in the troponin T levels and Framingham Risk Score is observed in this study. Conclusion: we conclude that there is a need for Vitamin E supplementation as there are possibilities of Vitamin E deficiency in diabetes mellitus. Vitamin E was also beneficial in reduction of cardiovascular risk.

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    Author(s) Name:

    D. Praveen1 , Puvvada Ranadheer Chowdary1 , M. Vijey Aanandhi 2 *

    Affiliation(s) Name:

    1 Research Scholar, School of Pharmaceutical Sciences, Vels Institute of Science Technology and Advanced Studies, Chennai, Tamil Nadu, India,

    2 Department of Pharmaceutical Chemistry and Analysis, School of Pharmaceutical Sciences, Vels Institute of Science Technology and Advanced Studies, Chennai, Tamil Nadu, India

    *Corresponding author: Dr. M. Vijey Aanandhi, Department of Pharmaceutical Chemistry and Analysis, School of Pharmaceutical Sciences, Vels Institute of Science Technology and Advanced Studies, Chennai, Tamil Nadu, India

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    Author:

    D. Praveen1 , Puvvada Ranadheer Chowdary1 , M. Vijey Aanandhi 2 *

    Title:Effects of Vitamin E supplementation on glycemic control and cardiovascular risk in patients with type II diabetes mellitus
    Journal:Drug Invention Today
    Vol(issue):12 (November )
    Year:2019
    Page No: (2529-2531)
  • Experimental Methods Keywords

    Methodology:A randomized parallel allocated study, fasting blood glucose, glycated hemoglobin, troponin T levels, lipid profile
    Research Materials:Vitamin E supplementation

Keywords

Cardiovascular risk Diabetes mellitus Vitamin E

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