Journal: Drug Invention Today

Article Id: JPRS-Pcol-00004432
Title: Clinical association of serum calcium levels in pre‑eclampsia and gestational hypertension patients: A prospective observational study
Category: Pharmacology
Section: Research Article
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    Aim and Objectives: The aim of the study was to evaluate the serum calcium levels and to study the role of calcium in pre-eclampsia and gestational hypertension. Materials and Methods: A prospective observational study design was conducted in 108 patients. Group A patients were diagnosed with pre-eclampsia and Group B patients were diagnosed with gestational hypertension. The study was conducted with the help of standard data entry forms, and serum calcium test was performed in both groups. The neonatal assessment was collected to study the role of calcium in pre-eclampsia and gestational hypertension. Results: Out of 108 patients, 54 patients were diagnosed with pre-eclampsia and 54 patients were diagnosed with gestational hypertension. Serum calcium level was found to be decreased in both groups. Management with calcium supplements (2.0 g elemental calcium/day) reduces preterm birth, birth defects, and cases of lower segment caesarian section based on neonatal assessment. Conclusion: Calcium supplements are safe and relatively cheap way of reducing the risk of gestational hypertension and pre-eclampsia, especially in women from communities with low dietary calcium.

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    Author(s) Name:

    S. Lakshmi Kanthamma1 , D. Praveen2 , P. Ranadheer Chowdary2 , M. Vijey Aanandhi 3 *

    Affiliation(s) Name:

    1 Department of Pharmacy Practice, School of Pharmaceutical Sciences, Vels Institute of Science Technology and Advanced Studies, Chennai, Tamil Nadu, India,

    2 Research Scholar, School of Pharmaceutical Sciences, Vels Institute of Science Technology and Advanced Studies, Chennai, Tamil Nadu, India,

    3 Department of Pharmaceutical Chemistry and Analysis, School of Pharmaceutical Sciences, Vels Institute of Science Technology and Advanced Studies, Chennai, Tamil Nadu, India

    *Corresponding author: Dr. M. Vijey Aanandhi, Department of Pharmaceutical Chemistry and Analysis, School of Pharmaceutical Sciences, Vels Institute of Science Technology and Advanced Studies, Chennai, Tamil Nadu, India.

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    Author:

    S. Lakshmi Kanthamma1 , D. Praveen2 , P. Ranadheer Chowdary2 , M. Vijey Aanandhi 3 *

    Title:Clinical association of serum calcium levels in pre‑eclampsia and gestational hypertension patients: A prospective observational study
    Journal:Drug Invention Today
    Vol(issue):12 (November )
    Year:2019
    Page No: (2532-2535)
  • Experimental Methods Keywords

    Methodology:A prospective observational study, Gestational hypertension, Neonatal assessment, Pre-eclampsia
    Research Materials:Calcium supplementation

Keywords

Calcium supplementation Gestational hypertension Neonatal assessment Pre-eclampsia

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