Journal: Drug Invention Today

Article Id: JPRS-Pcol-00004441
Title: Prevalence and association of Helicobacter pylori infection with gastritis and its age and sex distribution in a population of Karbala
Category: Pharmacology
Section: Research Article
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    Background: Helicobacter pylori is a pathogenic bacterium that parasitizes the gastric mucous layer and the epithelial lining of the stomach that causes duodenal ulcers, gastric ulcers, and cardiovascular disease among others, is found in about half of world’s population. The aim of this study is to find the prevalence and association of H. pylori infection with gastritis and its age and sex distribution in a population of Karbala. Materials and Methods: A 50 blood samples were collected from patients referred to Imam Al-Hussein Medical City in Karbala, from October 1, 2017, to January 1, 2018, with the mean ages of 1–75 years of both sexes. The samples were analyzed for the presence of H. pylori antibody in serum. Results: In the present study, determined the prevalence of H. pylori-associated gastritis in the population of Karbala is 94%. Chronic gastritis was found in 84% of patients with H. pylori infection and 16% of patients with gastritis of some other etiology.of 50 blood samples, 46% were seropositive with male and 48% female seroprevalences. The antibody prevalence was higher (30%) in middle-aged patients (16–45 years) than in younger patients (1–15 years) (8%) and older patients (61–75 years) (12%). There was no significant difference (P > 0.05) between both sexes regarding the incidence of gastritis with H. pylori. Conclusions: The most chronic gastritis infections are resulting from H. pylori. The middle-aged patients are the most susceptible to infection. There is no statistically significant difference in sex.

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    Author(s) Name:

    Eman J. Raheem Al-Ardawi 1* , Rasha M. Al-Hussaini 2 , Huda Mohammad Kadhim Al-asady1 , Atyaf Ali Sahib2 , Hussam H. Tizkam2

    Affiliation(s) Name:

    1 Department of Medical Laboratory Techniques, Al Safwa University College, Karbala, Iraq,

    2 Department of Pharmacy, Al Safwa University College, Karbala, Iraq

    *Corresponding author: Eman J. Raheem Al-Ardawi, Department of Medical Laboratory Techniques, Safwa University College, Karbala, Iraq.

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    Author:

    Eman J. Raheem Al-Ardawi 1* , Rasha M. Al-Hussaini 2 , Huda Mohammad Kadhim Al-asady1 , Atyaf Ali Sahib2 , Hussam H. Tizkam2

    Title:Prevalence and association of Helicobacter pylori infection with gastritis and its age and sex distribution in a population of Karbala
    Journal:Drug Invention Today
    Vol(issue):12 (November )
    Year:2019
    Page No: (2571-2574)
  • Experimental Methods Keywords

    Methodology:Gastritis, Helicobacter pylori, Prevalence and inflammation
    Research Materials: 50 blood samples, 1–75 years

Keywords

Gastritis Helicobacter pylori Prevalence and inflammation

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