Journal: Drug Invention Today

Article Id: JPRS-Pcol-00004461
Title: A prospective cross-sectional study on the clinical association of serum fibrinogen, platelets, and serum albumin in diabetic foot ulcer
Category: Pharmacology
Section: Research Article
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    Aim and Objectives: The main aim of the study was to find out the association of serum fibrinogen, serum albumin, and platelet values in diabetic foot ulcer patients. Materials and Methods: All the patients who were diagnosed with type II diabetes mellitus will be included in the study. Their serum levels of fasting blood sugar, post-prandial blood sugar, glycated hemoglobin (HbA1C), and associated blood parameters will be assessed. Diabetic foot ulcer is confirmed based on the signs and symptoms of the patients such as redness, tenderness, warmth, and swelling of the intensate foot or ankle. Serum fibrinogen, albumin, and platelet levels are measured. Results: Out of 108 patients, 54 were Type II diabetic without foot ulcer and 54 were Type II diabetic foot ulcer. Mean Serum fibrinogen of diabetic foot ulcer and diabetic is 412 ± 13.4 and 296.5 ± 13.6, respectively. Mean serum albumin of diabetic foot ulcer and diabetic is 2.7 ± 0.3 and 3.6 ± 0.6, respectively. The mean platelet value of diabetic foot ulcer and diabetic is 4.25 ± 1.25 and 2.75 ± 0.25, respectively. Conclusion: There has been a significant increase in serum fibrinogen, serum albumin, and platelet in diabetic patients. It can be clearly seen that elevated levels of these parameter have correlation with the severity of the disease.

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    Author(s) Name:

    N. Jayalakshmi 1 , D. Praveen2 , P. Ranadheer Chowdary2 , M. Vijey Aanandhi 3 *

    Affiliation(s) Name:

    1 Department of Pharmacy Practice, School of Pharmaceutical Sciences, Vels Institute of Science Technology and Advanced Studies, Chennai, Tamil Nadu, India,

    2 Research Scholar, School of Pharmaceutical Sciences, Vels Institute of Science Technology and Advanced Studies, Chennai, Tamil Nadu, India,

    3 Department of Pharmaceutical Chemistry and Analysis, School of Pharmaceutical Sciences, Vels Institute of Science Technology and Advanced Studies, Chennai, Tamil Nadu, India

    *Corresponding author: Dr. M. Vijey Aanandhi, Department of Pharmaceutical Chemistry and Analysis, School of Pharmaceutical Sciences, Vels Institute of Science Technology and Advanced Studies, Chennai, Tamil Nadu, India.

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    Author:

    N. Jayalakshmi 1 , D. Praveen2 , P. Ranadheer Chowdary2 , M. Vijey Aanandhi 3 *

    Title:A prospective cross-sectional study on the clinical association of serum fibrinogen, platelets, and serum albumin in diabetic foot ulcer
    Journal:Drug Invention Today
    Vol(issue):12 (November )
    Year:2019
    Page No: (2682-2685)
  • Experimental Methods Keywords

    Methodology:A prospective cross-sectional study
    Research Materials:patients with type II diabetes mellitus

Keywords

Diabetic foot ulcer Serum albumin and platelet Serum fibrinogen

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