Journal: Drug Invention Today

Article Id: JPRS-MSNS-00004509
Title: Evaluation of the antimicrobial activity of endodontic sealers against lactobacilli: An in vitro study
Category: Microbiological Study (on Natural/ Synthetic drug)
Section: Research Article
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    Aim: This study is done to find out the antimicrobial effect of sealers used in endodontic treatment against lactobacilli which is the major bacterial flora in patients with poor oral hygiene. The sealers which have good antimicrobial property prevent recolonization of the bacteria in the tooth cavity. Background: Microleakage is a common issue in endodontic treatment. This leads to the recolonization of the pulpal tissue by the salivary flora. An effective sealant that prevents the entry of salivary flora will be beneficial for a successful endodontic treatment. Apart from the sealing ability, the antimicrobial activity of the sealant will definitely reduce the microbial recolonization. Materials and Methods: An in vitro study is conducted to test the antimicrobial activity of the sealants. Agar well diffusion method is used in this study. The sealants are filled in with the cavity and the organism is spread on the agar surface. After incubation, the zone of inhibition is noted around the well and compared with different types of sealants. Results: The zone of inhibition produced by the three compounds tested is tabulated. It shows the mean zone at inhibition shown by the three compounds tested against lactobacilli. Among the three compounds tested the pit and fissure sealant has shown the maximum zone of inhibition. The other two sealants tested are found to be not effective against lactobacilli. Conclusion: Pit and fissure sealants have better antimicrobial property when compared to composite and GIC. Pit and fissure sealants have lesser susceptibility to bacteria and prevents recolonisation of bacteria.

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    Author(s) Name:

    A. Baala Vignesh, N. P. Muralidharan*

    Affiliation(s) Name:

    Department of Microbiology, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai Tamil Nadu, India

    *Corresponding author: N. P. Muralidharan, Department of Microbiology, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India.

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    Author:

    A. Baala Vignesh, N. P. Muralidharan*

    Title:Evaluation of the antimicrobial activity of endodontic sealers against lactobacilli: An in vitro study
    Journal:Drug Invention Today
    Vol(issue):11 (October [Special Issue 1])
    Year:2019
    Page No: (217-220)
  • Experimental Methods Keywords

    Methodology:Anti-microbial effects , An in vitro study
    Research Materials:endodontic sealers

Keywords

Anti-microbial effects Lactobacilli Pit and fissure sealants Secondary caries

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