Journal: Drug Invention Today

Article Id: JPRS-Pcol-00004518
Title: Drug abuse analysis using high-performance liquid chromatography with monolithic columns – A review
Category: Pharmacology
Section: Review Article
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    The problem of drug abuse has become one of the toughest problems for governments around the world. Based on the cases of drug abuse, a method of drug abuse analysis is needed to monitor its levels in the body. Several methods have been developed, but the most widely used is HPLC. The application of HPLC method requires fast and inexpensive testing techniques. In the past, particle columns were used for analysis many compounds. However, because of the tendency for blockages and backpressure to be very high, monolithic columns are used as an alternative for those problems. There are many applications and development of monolithic columns for drug abuse analysis. Monolithic columns are used for separation substance of drug abuse in their matrices. Based on the research that has been done, monolithic column shows better results compared to particle columns such as high selectivity, low cost, easy and simple preparation, and also minimizing high backpressure.

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    Author(s) Name:

    Belya Anindia Hermawan, Mutakin Mutakin, Aliya Nur Hasanah*

    Affiliation(s) Name:

    Department of Pharmaceutical Analysis and Medicinal Chemistry, Faculty of Pharmacy, Universitas Padjadjaran, Indonesia

    *Corresponding author: Aliya Nur Hasanah, Department of Pharmaceutical Analysis and Medicinal Chemistry, Faculty of Pharmacy, Universitas Padjadjaran, Indonesia.

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    Author:

    Belya Anindia Hermawan, Mutakin Mutakin, Aliya Nur Hasanah*

    Title:Drug abuse analysis using high-performance liquid chromatography with monolithic columns – A review
    Journal:Drug Invention Today
    Vol(issue):11 (December [ Special Issue 2])
    Year:2019
    Page No: (34-39)
  • Experimental Methods Keywords

    Methodology:HPLC
    Research Materials:Drug abuse analysis

Keywords

Drug abuse analysis Hybrid monolithic column Monolithic column Monolithic polymer column Monolithic silica column

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