Journal: Drug Invention Today

Article Id: JPRS-Pcol-00004650
Title: Hemostatic agents - A review
Category: Pharmacology
Section: Research Article
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  • Abstract

    Hemostasis is the normal physiological response that prevents significant blood loss following vascular injury. The process depends on an intricate series of events involving platelets, other cells, and the activation of specific blood proteins, known as coagulation factors. When blood vessel injury occurs, physiological hemostasis is triggered and the coagulation process occurs. Hemostasis serves to maintain the integrity of the circulatory system; however, the process can become imbalanced, leading to significant morbidity and mortality. The knowledge of the process of hemostasis is therefore important to understand the major disease states associated with thrombosis. As any surgeon would agree, hemostasis is of critical importance during all surgical procedures. A fundamental principle of good surgical technique is the minimization of blood loss, and present-day surgeons have a wide variety of agents and tools to aid them in this endeavor. Few urologic surgeons would be eager to undertake renal procedures without the ubiquitous electrosurgical unit. Although used less frequently than simple electrocautery, topical hemostatic agents are useful in minimizing blood loss and in turn surgical morbidity. Although no aid in hemostasis can negate the importance of good surgical technique, even the most talented surgeon has encountered persistent bleeding, which has required focused attention. Often a topical hemostatic agent is helpful in these situations, and the evolution of these agents is an interesting topic in surgical history.

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    Author(s) Name:

    Sivapriyah Kuppusamy1 , Mebin George Mathew1 *, Deepa Gurunathan2

    Affiliation(s) Name:

    1 Department of Research, Saveetha Dental College and Hospital, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India,

    2 Department of Pedodontics, Saveetha Dental College and Hospital, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India

    *Corresponding author: Dr. Mebin George Mathew, Department of Research, Saveetha Dental College and Hospital, Saveetha Institute of Medical and Technical Sciences, Saveetha University, 162, Poonamallee High Road, Chennai - 600 077, Tamil Nadu, India.

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    Author:

    Sivapriyah Kuppusamy1 , Mebin George Mathew1 *, Deepa Gurunathan2

    Title:Hemostatic agents - A review
    Journal:Drug Invention Today
    Vol(issue):12 (November [ Special Issue 1])
    Year:2019
    Page No: (155-158)
  • Experimental Methods Keywords

    Methodology:Thrombosis,Circulatory system, Hemostatic
    Research Materials:Hemostatic agents

Keywords

Circulatory system Hemostatic Knowledge Thrombosis

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