Journal: Drug Invention Today

Article Id: JPRS-P'Col-00004679
Title: Clinical profile of hospitalized children with febrile seizures
Category: Pharmacology
Section: Research Article
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    Objective: The objectives of this study were to evaluate the clinical profile, investigations, course in hospital, and outcome of children admitted with febrile seizures. Materials and Methods: A total of 70 children with febrile seizures were taken as study subjects. The study was conducted over 6 months, from June 2018 to November 2018. Clinical, laboratory, electroencephalography (EEG), and neuroimaging data were evaluated. Results: The children’s ages ranged between 7 and 70 months (mean = 20 and standard deviation [SD] = 14), and 58.5% were males. Majority of the hospitalized children (60 of 70) had complex febrile seizures (55%), were dull-looking (24.5%), suffered from status (17.5%), or positive meningeal irritation signs (4%). Electrolyte abnormalities were uncommon (10%), however, complete blood count was found to be abnormal in 45%, which increased the likelihood of receiving intravenous antibiotics (P = 0.01). Lumbar puncture was performed in those who demonstrated signs of meningeal irritation or those who were younger than 2 years of age. Magnetic resonance imaging brain was performed in 15.71% and EEG in 35.71%. Obtaining an EEG was less likely if the seizures were typical (13% vs. 50% in atypical, P = 0.002). Duration of hospitalization ranged between 1 and 14 days (mean = 4.7 and SD = 3.2), and only one child had meningitis, which was predicted clinically. Conclusions: Those children who were admitted frequently had complex febrile seizures, status epilepticus, or were ill-looking. Simple febrile seizures are generally investigated selectively. However, it was observed that the yield of investigations remains low and does not justify extensive work-up or prolonged hospitalization.

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    Author(s) Name:

    H. Javeri Aarti Harish, S. Jagadeeshwari*, S. Sundari

    Affiliation(s) Name:

    Department of Paediatrics, Sree Balaji Medical College and Hospital, Chennai, Tamil Nadu, India

    *Corresponding author: Dr. S. Jagadeeshwari, Department of Pediatrics, Sree Balaji Medical College and Hospital, Chennai, Tamil Nadu, India

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    H. Javeri Aarti Harish, S. Jagadeeshwari*, S. Sundari

    Title:Clinical profile of hospitalized children with febrile seizures
    Journal:Drug Invention Today
    Vol(issue):11 (December )
    Page No: (3268-3270)
  • Experimental Methods Keywords

    Methodology:Febrile seizures, Hospitalized, Clinical profile
    Research Materials: Children


 Children Febrile seizures Hospitalized

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