Article Id:JPRS-P'Col-00004679 Title:Clinical profile of hospitalized children with febrile seizures Category:Pharmacology Section:Research Article
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Objective:The objectives of this study were to evaluate the clinical profile, investigations, course in hospital, and outcome of children admitted with febrile seizures. Materials and Methods: A total of 70 children with febrile seizures were taken as study subjects. The study was conducted over 6 months, from June 2018 to November 2018. Clinical, laboratory, electroencephalography (EEG), and neuroimaging data were evaluated. Results: The children’s ages ranged between 7 and 70 months (mean = 20 and standard deviation [SD] = 14), and 58.5% were males. Majority of the hospitalized children (60 of 70) had complex febrile seizures (55%), were dull-looking (24.5%), suffered from status (17.5%), or positive meningeal irritation signs (4%). Electrolyte abnormalities were uncommon (10%), however, complete blood count was found to be abnormal in 45%, which increased the likelihood of receiving intravenous antibiotics (P = 0.01). Lumbar puncture was performed in those who demonstrated signs of meningeal irritation or those who were younger than 2 years of age. Magnetic resonance imaging brain was performed in 15.71% and EEG in 35.71%. Obtaining an EEG was less likely if the seizures were typical (13% vs. 50% in atypical, P = 0.002). Duration of hospitalization ranged between 1 and 14 days (mean = 4.7 and SD = 3.2), and only one child had meningitis, which was predicted clinically. Conclusions:Those children who were admitted frequently had complex febrile seizures, status epilepticus, or were ill-looking. Simple febrile seizures are generally investigated selectively. However, it was observed that the yield of investigations remains low and does not justify extensive work-up or prolonged hospitalization.
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Author(s) Name:
H. Javeri Aarti Harish, S. Jagadeeshwari*, S. Sundari
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Department of Paediatrics, Sree Balaji Medical College and Hospital, Chennai, Tamil Nadu, India
*Corresponding author:Dr. S. Jagadeeshwari, Department of Pediatrics, Sree Balaji Medical College and Hospital, Chennai, Tamil Nadu, India