Journal: Drug Invention Today

Article Id: JPRS-P'ceu-00004898
Title: A perspective view on nanosponge drug delivery system
Category: Pharmaceutics
Section: Review Article
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    Targeting drug delivery has long been a problem for medical researchers to get them to their right place in the body and how to control the release of the drug to prevent overdose. The development of new and complex molecules called nanosponges has the potential to solve these problems. Nanosponge is a novel and emerging technology which play a key role in targeting drug delivery in a controlled manner. It is a new class of materials and made of microscopic particles with few nanometers wide cavities in which a large variety of substances can be encapsulated. To overcome the problems of bioavailability, of which nanosponge is an advanced drug delivery system which offers diverse advantages than the other available systems. Nanosponge is based on nano, polymer-based spheres that can suspend or entrap a wide variety of substances and then be incorporated into a formulated product such as a gel, lotions, cream, ointments, liquid, or powder. This technology offers entrapment of ingredients and thus reduced side effects, improved stability, increases elegance, and enhanced formulation flexibility. This review article deals with the general introduction of nanosponges, characteristic features of nanosponges, their advantages, disadvantages, preparation methodologies, factors affecting on their preparation, and with some referential examples of nanosponge drugs.

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    Author(s) Name:

    S. Dhanalakshmi 1 *, N. Harikrishnan2 , B. A. Tanisha3 , G. Pooja3 , L. Yuvarani 3 , A. Sajina Begum3 , M. Tharun Kumar3 , A. Santhosh3

    Affiliation(s) Name:

    1 Department of Pharmacognosy, Faculty of Pharmacy, Dr. M.G.R. Educational and Research Institute (Deemed to be University), Chennai, Tamil Nadu, India,

    2 Department of Pharmaceutical Chemistry and Analysis, Faculty of Pharmacy, Dr. M.G.R. Educational and Research Institute (Deemed to be University), Chennai, Tamil Nadu, India,

    3 Pharma Buddy, Faculty of Pharmacy, Dr. M.G.R. Educational and Research Institute (Deemed to be University), Chennai, Tamil Nadu, India

    *Corresponding author: S. Dhanalakshmi, Department of Pharmacognosy, Faculty of Pharmacy, Dr. M.G.R. Educational and Research Institute (Deemed to be University), Velappanchavadi, Chennai - 600 076, Tamil Nadu, India.

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    Author:

    S. Dhanalakshmi 1 *, N. Harikrishnan2 , B. A. Tanisha3 , G. Pooja3 , L. Yuvarani 3 , A. Sajina Begum3 , M. Tharun Kumar3 , A. Santhosh3

    Title:A perspective view on nanosponge drug delivery system
    Journal:Drug Invention Today
    Vol(issue):14 (March)
    Year:2020
    Page No: (438-445)
  • Experimental Methods Keywords

    Methodology:Nanosponge, Nanotechnology, Solubility, Targeted drug delivery
    Research Materials:Cyclodextrin

Keywords

Cyclodextrin Nanosponge Nanotechnology Solubility Targeted drug delivery

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