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Abstract

Targeting drug delivery has long been a problem for medical researchers to get them to their right place in the body and how to control the release of the drug to prevent overdose. The development of new and complex molecules called nanosponges has the potential to solve these problems. Nanosponge is a novel and emerging technology which play a key role in targeting drug delivery in a controlled manner. It is a new class of materials and made of microscopic particles with few nanometers wide cavities in which a large variety of substances can be encapsulated. To overcome the problems of bioavailability, of which nanosponge is an advanced drug delivery system which offers diverse advantages than the other available systems. Nanosponge is based on nano, polymer-based spheres that can suspend or entrap a wide variety of substances and then be incorporated into a formulated product such as a gel, lotions, cream, ointments, liquid, or powder. This technology offers entrapment of ingredients and thus reduced side effects, improved stability, increases elegance, and enhanced formulation flexibility. This review article deals with the general introduction of nanosponges, characteristic features of nanosponges, their advantages, disadvantages, preparation methodologies, factors affecting on their preparation, and with some referential examples of nanosponge drugs.

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	JPR Solutions

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