Journal: Journal of Pharmacy Research
Title: In vitro antioxidant and anticholinesterase activity of Acorus calamus and Nardostachys jatamansi rhizomes
Category: Pharmacognosy and Herbal Drugs related study
Section: Research Article
- Abstract
- Audio Abstract
- Authors
- Pdf File
- Citation
- My Reference
- Methodology
-
Abstract
The present study evaluated the free radical scavenging and anticholinesterase activity of the methanolic extracts of Acorus calamus (ACME) and Nardostachys jatamansi (NJME) rhizomes in vitro. In addition, total phenolics (TP) were also estimated. NJME contained significantly higher (p =0.05) phenolics (37 μg GAE/mg) than ACME (23μg GAE/mg). Consequently, NJME exhibited significantly higher (p =0.05) radical scavenging activity than ACME and BHT, a synthetic antioxidant. Further, the IC50 values were 704, 237 & 335 μg/ml for ACME, NJME and BHT respectively. In case of anticholinesterase activity also NJME exhibited significantly higher (p =0.05) activity with lower IC50 value than ACME. However, the anticholinesterase activity of both ACME and NJME were significantly lower (p =0.05) than neostigmine, a standard drug wherein, neostigmine exhibited significantly lower (p =0.05) IC50 value than ACME and NJME. Furthermore, a significant correlation between the total phenolic content, antioxidant and anticholinesterase activities of both the extracts indicating that total phenolics might be responsible for the observed antioxidant and anticholinesterase activities.This is the first report in this direction.
-
Abstract Audio
About the authors and Affiliations
Author(s) Name: Faiyaz Ahmeda*, Narendra Sharath Chandra J.Nb, Asna Urooja and Rangappa K.Sb
Affiliation(s) Name: aDepartment of Studies in Food Science and Nutrition, University of Mysore, Mysore-570006, India.
bDepartment of Studies in Chemistry, University of Mysore, Mysore-570006, India.
Received on: 22-09-2008; Accepted on: 04-01-2009-
View Article File in pdf format.
Article File
-
View Article Citation Here.
8 View More -
How to Cite my Article.
Author: Faiyaz Ahmeda*, Narendra Sharath Chandra J.Nb, Asna Urooja and Rangappa K.Sb
Title: In vitro antioxidant and anticholinesterase activity of Acorus calamus and Nardostachys jatamansi rhizomes Journal: Journal of Pharmacy Research Vol(issue): 2 (May) Year: 2009 Page No: (830-833) -
Experimental Methods Keywords
Methodology: In vitro antioxidant , anticholinesterase activity Research Materials: Acorus calamus , Nardostachys jatamansi rhizomes
Keywords
Our Services
- Medicinal uses of banana (Musa paradisiaca)
- GC-MS study and phytochemical profiling of Mimosa pudica Linn.
- Biodegradable plastic production from corn starch
- Hypovolemic shock - A review
- Development and Validation of Stability Indicating UV Spectrophotometric Method for the Estimation of Sitagliptin Phosphate in Bulk and Tablet Dosage Form
- Studies on antifungal properties of Talisadi Churna on human pathogens
- Design, Evaluation, Parameters and Marketed Products of transdermal patches: A Review
- Extraction of Betacyanin from Red Beet root (Beta vulgaris L.) and to evaluate its antioxidant potential antioxidant potential
- Review On: Fast Dissolving Tablet
- Analysis of Amino Acids By Paper Chromatography
- Effect of stress on academic performance of students in different streams
- A comparative study of pregabalin and gabapentin combinations in type 2 diabetic neuropathy patients
- In-vitro anti-arthritic activity of Abutilon indicum (Linn.) Sweet
- Awareness of effects of sleep deprivation among college students
- Awareness of selfie addiction among teenagers: A questionnaire-based study
- Impurity profile- A review
- Plant natural products: Their pharmaceutical potential against disease and drug resistant microbial pathogens
- Soxhlet Extraction of Neem seed (Azadirachta indica A. Juss) Using Hexane as a Solvent.
- Pharmacognostic Study Of Plant Euphorbia hirta L
- Standardization of Nandhi Mezhugu, a poly herbomineral Siddha formulation
- Awareness on soil pollution among school students
- Anti-oxidant activities of Biopolymeric Nanoparticles: Boon or Bane!
- Application of nanotechnology for Ayurvedic drugs and formulations
- Physiological changes in pregnancy
- Formulation and evaluation of Aloe vera gels
- Phytochemical Analysis of Cocos nucifera L
- Antibiofilm activity of temu kunci (Boesenbergia rotunda), an Indonesian medicinal plant extract, against root canal pathogens
- Study the Effect of Phytochemical Constituents of Piper betel Leaves Extracts on Liver Disorders by in vivo Model
- Excessive usage of headphones among college students and their effects
- Risk factors and protective factors of mental health during coronavirus disease-19 outbreak and lockdown in adult Indian population – A cross-sectional study