Journal: Journal of Pharmacy Research
Title: Wound healing activity of the leaves of Tribulus terrestris (linn) aqueous extract in rats
Category: Pharmacology
Section: Research Article
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Abstract
The leaves of Tribulus terrestris(zygophyllaceae) are used traditionally in the folklore for the treatment of various kinds of wounds. The present study was undertaken to verify the effect of the leaves of T. terrestris on experimentally induced excision wound, incision wound and burn wound models in rats. Aloe vera was used as standard wound healing agent. A formulation of aqueous leaves extract in carbopol at 2.5% and 5% concentrations were prepared and applied to the wounds. In the excision and burn wound models, the animal showed significant reduction in period of epithelization and wound contraction (50%). In the incision wound model a significant increase in the breaking strength was observed. The results suggest that T. terrestris aqueous leaves extract applied topically possess wound healing activity.
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About the authors and Affiliations
Author(s) Name: *1J. John Wesley, 2A.J.M. Christina, 2N. Chidambaranathan, 2K. Ravikumar
Affiliation(s) Name: *1Dept. of Pharmacology, Arulmigu Kalasalingam college of Pharmacy, Krishnankoil 626 190.
2Dept. of Pharmacology, K.M. college of Pharmacy, Uthangudi, Madurai 625107.
Received on: 25-09-2008; Accepted on: 27-01-2009-
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Author: *1J. John Wesley, 2A.J.M. Christina, 2N. Chidambaranathan, 2K. Ravikumar
Title: Wound healing activity of the leaves of Tribulus terrestris (linn) aqueous extract in rats Journal: Journal of Pharmacy Research Vol(issue): 2 (May) Year: 2009 Page No: (841-843) -
Experimental Methods Keywords
Methodology: Burn wound, excision wound, incision wound, Research Materials: Tribulus terrestris linn.
Keywords
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