Journal: Journal of Pharmacy Research

Article Id: JPRS-P'Col-0000503
Title: Wound healing activity of the leaves of Tribulus terrestris (linn) aqueous extract in rats
Category: Pharmacology
Section: Research Article
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  • Abstract

    The leaves of Tribulus terrestris(zygophyllaceae) are used traditionally in the folklore for the treatment of various kinds of wounds. The present study was undertaken to verify the effect of the leaves of T. terrestris on experimentally induced excision wound, incision wound and burn wound models in rats. Aloe vera was used as standard wound healing agent. A formulation of aqueous leaves extract in carbopol at 2.5% and 5% concentrations were prepared and applied to the wounds. In the excision and burn wound models, the animal showed significant reduction in period of epithelization and wound contraction (50%). In the incision wound model a significant increase in the breaking strength was observed. The results suggest that T. terrestris aqueous leaves extract applied topically possess wound healing activity.

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    Author(s) Name:

    *1J. John Wesley, 2A.J.M. Christina, 2N. Chidambaranathan, 2K. Ravikumar

    Affiliation(s) Name:

    *1Dept. of Pharmacology, Arulmigu Kalasalingam college of Pharmacy, Krishnankoil 626 190.
    2Dept. of Pharmacology, K.M. college of Pharmacy, Uthangudi, Madurai 625107.


    Received on: 25-09-2008; Accepted on: 27-01-2009

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    Author:

    *1J. John Wesley, 2A.J.M. Christina, 2N. Chidambaranathan, 2K. Ravikumar
    Title:Wound healing activity of the leaves of Tribulus terrestris (linn) aqueous extract in rats
    Journal:Journal of Pharmacy Research
    Vol(issue):2 (May)
    Year:2009
    Page No: (841-843)

  • Experimental Methods Keywords

    Methodology:Burn wound, excision wound, incision wound,
    Research Materials:Tribulus terrestris linn.

Keywords

Burn wound excision wound incision wound Tribulus terrestris linn.

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