Journal: Journal of Pharmacy Research
Title: Simultaneous determination of Finasteride and Tamsulosin in pharmaceutical preparations by ratio derivative spectroscopy
Category: Quality Assurance
Section: Research Article
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Abstract
Simple, accurate, precise, and sensitive spectrophotometric method for simultaneous estimation of Tamsulosin(TAM) and Finasteride(FINA) in combined tablet dosage form have been developed and validated. The ratio derivative spectroscopic method involves measurement of first derivative amplitude of ratio spectra at 240.01nm for FINA and 229.91 nm for TAM as two wavelengths for estimation. Beer’s law is obeyed in the concentration range of 2-10 and 25-125 μg/mL for TAM and FINA, respectively.
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About the authors and Affiliations
Author(s) Name: Atul H. Kategaonkar1, Dhaval M. Patel, Vishnu P. Choudhari1*, Bhanudas S. Kuchekar1, Ana G. Nikalje2.
Affiliation(s) Name: 1. Pharmaceutical Analysis and Quality Assurance Dept.,MAEER’S Maharashtra Institute of Pharmacy, S.No. 124, MIT Campus, Paud Road, Kothrud, Pune-411038, India.
2. Post-graduate Department of Pharmaceutical Chemistry, Y.B. Chavan College of Pharmacy, Dr. Rafiq Zakaria Campus, Rauza Bagh, Aurangabad.431001. MS. India
Received on: 27-02-2009; Accepted on: 29-04-2009-
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How to Cite my Article.
Author: Atul H. Kategaonkar1, Dhaval M. Patel, Vishnu P. Choudhari1*, Bhanudas S. Kuchekar1, Ana G. Nikalje2.
Title: Simultaneous determination of Finasteride and Tamsulosin in pharmaceutical preparations by ratio derivative spectroscopy Journal: Journal of Pharmacy Research Vol(issue): 2 (June) Year: 2009 Page No: (1065-1067) -
Experimental Methods Keywords
Methodology: Simultaneous determination,Spectroscopy Research Materials: Tamsulosin, Finasteride
Keywords
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