Journal: Drug Invention Today

Article Id: JPRS-MSNS-00005441
Title: Antimicrobial effect of garlic on oral microbes – An in vitro study
Category: Microbiological Study (on Natural/ Synthetic drug)
Section: Research Article
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    Introduction: There are many different treatment modalities for treating the microorganisms present in the oral cavity. Due to the frequent use and misuse of the therapeutic agents has led to the occurrence of adverse effects and development of resistant strains. Hence, the need for natural medications is in higher demand. Garlic and ginger are the medicinal plants which are known for their antimicrobial effects against the various pathogens. Garlic and ginger have a wide variety of properties such as antibacterial, anti-inflammatory, and antioxidant properties. This article is mainly focused to determine the antibacterial effect of ginger and garlic on subgingival plaque of periodontitis patients. Materials and Methods: This study is conducted with the ethanolic extract of garlic. The extract is used undiluted. Sterile antibiotic disks were impregnated with 15 µL of the extract. Standard strain of coagulase-negative Staphylococcus and Lactobacillus was grown on surface agar culture. They were suspended separately in normal saline with turbidity matching 0.5 McFarland Standard. These standard strains were coated on nutrient agar on Petri dish. Then, the disk containing the garlic extract was placed on it. Then, the plates were incubated at 37°C overnight. After incubation, the plates were examined for zone of inhibition. Results: After 24 h, on examination there was no zone of inhibition on the agar plates for both the organisms-lactobacillus and coagulase-negative Staphylococcus. Conclusion: All the isolates used, in our study, were not susceptible to the garlic extracts.

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    Author(s) Name:

    Ruksana Sheik, Jaiganesh Ramamurthy*

    Affiliation(s) Name:

    Department of Periodontics, Saveetha Dental College and Hospital, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India

    *Corresponding author: Jaiganesh Ramamurthy, Department of Periodontics, Saveetha Dental College and Hospital, Saveetha Institute of Medical and Technical Sciences, Saveetha University, 162, Poonamallee High Road, Chennai - 600 077, Tamil Nadu, India.

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    Author:

    Ruksana Sheik, Jaiganesh Ramamurthy*

    Title:Antimicrobial effect of garlic on oral microbes – An in vitro study
    Journal:Drug Invention Today
    Vol(issue):14 (March)
    Year:2020
    Page No: (197-201)
  • Experimental Methods Keywords

    Methodology:Antimicrobial effect
    Research Materials:Garlic

Keywords

Antimicrobial Garlic Microbes Oral Staphylococcus

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