Journal: Journal of Pharmacy Research
Title: Phytosomes: a potential phyto-phospholipid carriers for herbal drug delivery
Category: Pharmaceutics
Section: Review Article
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Abstract
The potential uses of large number of herbal drugs are limited due to their poor absorption and poor bioavailability after oral administration. The bioavailability can be improved by formulating a appropriate drug delivery system, which can enhance the rate and the extent of drug absorption across the lipoid biomembrane. Phospholipids based drug delivery system have been found promising for better and effective delivery of drug and providing much appropriate systematic drug delivery. The phospholipid molecular structure includes a water-soluble head and two fat-soluble tails, because of this dual solubility, the phospholipid acts as an effective emulsifier, which is also one of the chief components of the membranes in our cells. “Phytosome” is formed by complexing the polyphenolic phytoconstituents in molar ratio with phosphatidylcholine. Phytosomes are advanced forms of herbal products that are better absorbed, utilized, and as a result produce better drug delivery than conventional herbal extracts. This article reviews the current trends in phytosomes drug delivery.
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About the authors and Affiliations
Author(s) Name: Nitesh S Chauhan*1, Gowtham Rajan2, B. Gopalakrishna1
Affiliation(s) Name: 1Department of Pharmaceutics, R R College of Pharmacy, Bangalore-560090
2Departmet of Pharmacy, Karpagam University, Coimbatore-641 021
Received on: 27-02-2009; Accepted on: 29-04-2009-
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Author: Nitesh S Chauhan*1, Gowtham Rajan2, B. Gopalakrishna1
Title: Phytosomes: a potential phyto-phospholipid carriers for herbal drug delivery Journal: Journal of Pharmacy Research Vol(issue): 2 (July) Year: 2009 Page No: (1267-1270) -
Experimental Methods Keywords
Methodology: Drug Delivery Research Materials: Phytosomes
Keywords
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