Journal: Journal of Pharmacy Research
Title: Anti-nociceptive Activity of the Fruits of Swietenia macrophylla King.
Category: Pharmacology
Section: Research Article
- Abstract
- Audio Abstract
- Authors
- Pdf File
- Citation
- My Reference
- Methodology
-
Abstract
Fruits of Swietenia macrophylla King (Meliaceae) are used in Malay folk medicine as pain killer. The antinociceptive effect of ethanol and aqueous extracts was assessed by oral administration in acetic acid induced writhing, tail immersion and hot plate tests in mice. The ethanol extract 200 mg/kg treated group reduces the number of writhing on animal model, showed powerful anti-nociceptive effect (P < 0.01). Also the significant (P < 0.01) analgesic activity of S. macrophylla ethanolic extract at the dose of 200 mg/kg was further confirmed by tail-flick response and hot-plate response (P < 0.01).S. macrophylla extract produce analgesic in chemical and thermal pain models through a mechanism partially linked to either lipooxygenase and/or cyclooxygenase via the arachidonic acid cascade and/or opioid receptors. Our results corroborate the analgesic effects of S.macrophylla, and confirm its traditional use for treating pain.
-
Abstract Audio
About the authors and Affiliations
Author(s) Name: Amitava Das *, J.Anbu Jeba Sunilson, Rejitha Gopinath, Suraj Radhamani, Kiran Nilugal
Affiliation(s) Name: *School of Pharmacy, Masterskill University College of Health Sciences, 43200, Batu 9, Cheras, Selangor, Malaysia.
Received on: 27-04-2009; Accepted on: 29-07-2009-
View Article File in pdf format.
Article File
-
View Article Citation Here.
10 View More -
How to Cite my Article.
Author: Amitava Das *, J.Anbu Jeba Sunilson, Rejitha Gopinath, Suraj Radhamani, Kiran Nilugal
Title: Anti-nociceptive Activity of the Fruits of Swietenia macrophylla King. Journal: Journal of Pharmacy Research Vol(issue): 2 (September) Year: 2009 Page No: (1367-1369) -
Experimental Methods Keywords
Methodology: Anti-nociceptive Activity Research Materials: Swietenia macrophylla
Keywords
Our Services
- Current Trends in Herbal Medicines
- Extraction of Betacyanin from Red Beet root (Beta vulgaris L.) and to evaluate its antioxidant potential antioxidant potential
- Formulation and evaluation of Aloe vera gels
- Modified release dosage form and drug delivery
- Effect of Kapalbhati Pranayama in the blood sugar level in diabetic patients
- Awareness on soil pollution among school students
- In vitro-In vivo Correlation (IVIVC): A Review
- Estimation of Tizanidine HCl by UV-Spectrophotometric Method
- Lemongrass in dental health
- Design, Evaluation, Parameters and Marketed Products of transdermal patches: A Review
- Sodium alginate: the wonder polymer for controlled drug delivery
- A review on cataract and its herbal treatments
- A comparative study of common technical document in different regulated market
- Academic stress and its effect on medical students’ mental health status
- Analysis of Amino Acids By Paper Chromatography
- Plant natural products: Their pharmaceutical potential against disease and drug resistant microbial pathogens
- Chromolaena odorata (L.) : An Overview
- Formulation design and development of Orodispersible tablets of Levetiracetam
- A comparative study on the efficacy of lycopene and quercetin in oral submucous fibrosis cell lines
- Impact of poultry consumption by adolescent females – An analytical study
- Comparitive study on phytochemicals from leaves of Mentha piperita (Mint), Psidium guajava (Guava) and Moringa oleifera (Drumstick)
- Cow Urine Concentrate : A potent agent with Antimicrobial and Anthelmintic activity
- Impurity profile- A review
- Evaluation of Anti-Inflammatory Activity of Methanol Extract of Abutilon indicum And Pedalium murex- A Comparative Study
- Effect of stress on academic performance of students in different streams
- In silico study of Rumput Fatimah (Anastatica hierochuntica L.) estrogenic activities and its potential as phytoestrogens
- Review on Stereospermum suaveolens DC : A Potential Herb
- GC-MS study and phytochemical profiling of Mimosa pudica Linn.
- Standardization of Nandhi Mezhugu, a poly herbomineral Siddha formulation
- Validation of water system: A review