Journal: Journal of Pharmacy Research
Title: Fast dissolving Drug delivery system : Review Article
Category: Pharmaceutics
Section: Review Article
- Abstract
- Audio Abstract
- Authors
- Pdf File
- Citation
- My Reference
- Methodology
-
Abstract
Swallowing a pill is a major difficulty encountered in case of geriatric and pediatric patient which leads to poor patient compliance due to unpalatable taste of drug. To troubleshoot these problems a new dosage form known as fast-dissolving tablet (FDT), has been developed which rapidly disintegrate and dissolve in saliva. FDT are intended and designed to disintegrate and dissolve in saliva and then easily swallowed without need of water which is a major benefit over conventional dosage form. These dosage forms are also used to attain instant a higher concentration of drug in body for immediate actions. Fast dissolving tablets can be prepared by various conventional methods like direct compression, wet granulation, moulding, spray drying, freeze drying, and sublimation. In 1986, the first lyophilized fast-dissolving technology Zydis® was introduced by Cardinal formerly R. P. Scherer and after that there was a continuous growth in names , technologies & patented technology by different companies. Now a number of fast-dissolving formulations are in market like Claritin Reditab (Manufacturer R.P.Scherr,Inc.), Risperdal M-Tab (Manufacturer Janseen pharmaceutics.), Tempra Quicklets (Manufacturer Cima Labs,inc) and the technology is still improving. Present review focuses on the need of FDTs, pros and cons, drugs/marketed preparations, manufacturing process involved, evaluation of products and future trend.
-
Abstract Audio
About the authors and Affiliations
Author(s) Name: Sunita Kumari*, Sharad Visht, Pramod Kumar Sharma, Rakesh Kumar Yadav
Affiliation(s) Name: Department of Pharmaceutical Technology,Meerut Institute of Engineering and Technology, Meerut, India.
*Corresponding author.
Sunita Kumari
Department of Pharmaceutical Technology,
Meerut Institute of Engineering and Technology, Meerut, India.
Received on: 16-03-2010; Revised on: 15-04-2010; Accepted on:18-05-2010-
View Article File in pdf format.
Article File
-
View Article Citation Here.
24 View More -
How to Cite my Article.
Author: Sunita Kumari*, Sharad Visht, Pramod Kumar Sharma, Rakesh Kumar Yadav
Title: Fast dissolving Drug delivery system : Review Article Journal: Journal of Pharmacy Research Vol(issue): 3 (June) Year: 2010 Page No: (1444-1449) -
Experimental Methods Keywords
Methodology: Fast dissolving Drug delivery system Research Materials: synthetic drugs
Keywords
Our Services
- Analysis of Amino Acids By Paper Chromatography
- Photodegradation and Photostabilization of Ascorbic Acid in Pharmaceutical Preparations
- Advances in medical application of Swertia chirata plant extract in the treatment of diabetics: A brief review
- GC-MS study and phytochemical profiling of Mimosa pudica Linn.
- Extraction of Betacyanin from Red Beet root (Beta vulgaris L.) and to evaluate its antioxidant potential antioxidant potential
- Effect of stress on academic performance of students in different streams
- Variation in salivary pH and buffering capacity of saliva in normal and diabetes mellitus patients - A pilot study
- Awareness on soil pollution among school students
- Antimicrobial activity of seaweeds Gracillaria, Padina and Sargassum sps. on clinical and phytopathogensSubba Rangaiah G, Lakshmi P* and Manjula E
- Formulation and evaluation of topical gel of diclofenac sodium using different polymers
- Quality assessment of a traditional oil based Ayurvedic formulation :Yashtimadhuka Taila
- Awareness of effects of sleep deprivation among college students
- Review On: Fast Dissolving Tablet
- Current Trends in Herbal Medicines
- Review on various techniques of solubility enhancement of poorly soluble drugs with special emphasis on solid dispersion
- Validation of Uv Spectrophotometric method for estimation of Levocetirizine Dihydrochloride in bulk and pharmaceutical formulation
- Simultaneous estimation of Sitagliptin and Metformin hydrochloride in bulk and dosage form by UV spectrophotometry
- Oral dissolving films of Celecoxib inclusion complexes using Musa paradisiaca as super disintegrant in treatment of Psoriatic arthritis
- Phytochemical screening and in vitro anti-dandruff activities of bark extracts of neem (Azadirachta indica)
- Orally Disintegrating Tablets: A Review
- Formulation of olmesartan medoxomil nanoparticulate drug delivery for enhancement of oral bioavailability by Ionic-Gelation Techniques
- QbD Approach for Analytical Method Development and Validation of Melatonin by spectroscopic Method
- Antidiabetic, antioxidant, and antibacterial potentials of endophytic fungi isolated from Cassia fistula
- An overview on nanocarrier technology- Aquasomes
- Development and Validation of Stability Indicating UV Spectrophotometric Method for the Estimation of Sitagliptin Phosphate in Bulk and Tablet Dosage Form
- Pharmacognostic, Phytochemical & Quantitative Investigation of Saraca asoca leaves
- Abrus precatorius Linnaeus: A Phytopharmacological Review
- Antidiabetic activity of Lantana camara Linn fruits in normal and streptozotocin-induced diabetic rats
- Application of nanotechnology for Ayurvedic drugs and formulations
- A short review on smoker’s melanosis