Journal: Journal of Pharmacy Research
Title: In vitro anti-Candida activity of Calotropis gigantea.
Category: Pharmaceutical Biotechnology
Section: Research Article
- Abstract
- Audio Abstract
- Authors
- Pdf File
- Citation
- My Reference
- Methodology
-
Abstract
The aim of this study is to screen leaves of Calotropis gigantea for the anti-Candida properties against four clinical isolates of Candida. Aqueous, methanol, ethanol and petroleum ether extracts of the leaves of Calotropis gigantea were screened against clinical isolate of Candida albicans, C. parapsilosis, C. tropicalis and C. krusei. The in vitro anti-Candida assay was performed by agar well diffusion method in potato dextrose agar (PDA). Minimal inhibitory concentration (MIC) test was performed by modified agar well diffusion assay in PDA. The inhibitory effect of aqueous extract on all four tested Candida species was significantly higher than the methanol, ethanol and petroleum ether extracts. Aqueous extract showed low MIC values against C. tropicalis (125 μg/ml), C. krusei (250 μg/ml) and C. albicans (500 ìg/ml), followed by the methanol extract against C. tropicalis, C. krusei (500 μg/ml) and petroleum ether extract against C. tropicalis (500 μg/ml). The results prove Calotropis gigantea as a potent source of natural anti-Candida compounds.
Cite this article :Gaurav Kumar, Loganathan Karthik and Kokati Venkata Bhaskara Rao,In vitro anti-Candida activity of Calotropis gigantea,Journal of Pharmacy Research 2010, 3(3),539-542.
.Journal of Pharmacy Research 2010, 3(3),539-542 -
Abstract Audio
About the authors and Affiliations
Author(s) Name: Gaurav Kumar, Loganathan Karthik and Kokati Venkata Bhaskara Rao*.
Affiliation(s) Name: *Environmental Biotechnology Division, School of Bioscience and Technology, VIT University, Vellore, TN - 632 014, India
*Corresponding author.
Dr. Kokati Venkata Bhaskara Rao
Assistant Professor (Senior), Environmental Biotechnology Division
School of Bioscience and Technology
VIT University, Vellore, TN - 632 014, India
Received on: 17-11-2009; Revised on: 19-12-2009; Accepted on:08-02-2010-
View Article File in pdf format.
Article File
-
View Article Citation Here.
47 View More -
How to Cite my Article.
Author: Gaurav Kumar, Loganathan Karthik and Kokati Venkata Bhaskara Rao*.
Title: In vitro anti-Candida activity of Calotropis gigantea. Journal: Journal of Pharmacy Research Vol(issue): 3 (March) Year: 2010 Page No: (539-542) -
Experimental Methods Keywords
Methodology: minimal inhibitory concentration; well diffusion method. Research Materials: Calotropis gigantea
Keywords
Our Services
- Citric acid production from cane molasses using submerged fermentation by Aspergillus niger ATCC9142
- Medicinal uses of banana (Musa paradisiaca)
- Review On: Fast Dissolving Tablet
- Current Trends in Herbal Medicines
- Hypovolemic shock - A review
- Development and Validation of Stability Indicating UV Spectrophotometric Method for the Estimation of Sitagliptin Phosphate in Bulk and Tablet Dosage Form
- Effect of music on academic performance of college students
- Formulation and evaluation of Aloe vera gels
- Design, Evaluation, Parameters and Marketed Products of transdermal patches: A Review
- Analysis of Amino Acids By Paper Chromatography
- Impurity profile- A review
- Awareness of effects of sleep deprivation among college students
- In-vitro anti-arthritic activity of Abutilon indicum (Linn.) Sweet
- Soxhlet Extraction of Neem seed (Azadirachta indica A. Juss) Using Hexane as a Solvent.
- QbD Approach for Analytical Method Development and Validation of Melatonin by spectroscopic Method
- Plant natural products: Their pharmaceutical potential against disease and drug resistant microbial pathogens
- Awareness on soil pollution among school students
- Antibiofilm activity of temu kunci (Boesenbergia rotunda), an Indonesian medicinal plant extract, against root canal pathogens
- Effect of proprioception training and backward walking training among diabetic neuropathy patients
- A comparative study of pregabalin and gabapentin combinations in type 2 diabetic neuropathy patients
- Structural Elucidation of Potential Impurities of Raloxifene Hydrochloride by LC/ESI-MS and NMR#
- Study the Effect of Phytochemical Constituents of Piper betel Leaves Extracts on Liver Disorders by in vivo Model
- Extraction of Betacyanin from Red Beet root (Beta vulgaris L.) and to evaluate its antioxidant potential antioxidant potential
- Pharmacognostic Study Of Plant Euphorbia hirta L
- Studies on antifungal properties of Talisadi Churna on human pathogens
- Anti-oxidant activities of Biopolymeric Nanoparticles: Boon or Bane!
- A review on cellulose and its utilization from agro‑industrial waste
- Sleep disorder in adolescent age
- Physalis peruviana Linn. fruit extract improves insulin sensitivity and ameliorates hyperglycemia in high-fat diet low dose STZ-induced type 2 diabetic rats
- Anti-inflammatory activity of aqueous extract of Cinnamomum tamala leaves by in vivo and in vitro methods