Journal: Drug Invention Today
Title: Antibacterial activity of ethanolic leaf extract of Rauwolfia tetraphylla (Apocyanaceae) and its bioactive compound reserpine
Category: Microbiological Study (on Natural/ Synthetic drug)
Section: Research Article
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Abstract
In vitro antibacterial activity of ethanolic leaf extract of Rauwolfia tetraphylla was studied against selected pathogenic bacteria Bacillus cereus, Escherichia coli, Staphylococcus aureus and Yersinia enterocolitica by disc diffusion assay. Bioactive compound reserpine was isolated from the leaf. The results revealed that the ethanolic leaf extract and reserpine compound are potent in inhibiting these bacteria which cause gastroenteritis in human population. This work highlights that the inhibitory effect is on par with standard antibiotics.
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About the authors and Affiliations
Author(s) Name: M. N. Abubacker1 and S. Vasantha2
Affiliation(s) Name: 1PG and Research Dept of Botany, National College, Tiruchirappalli - 620 001, India.
2PG and Research Dept of Botany, A.V.V.M. Sri Pushpam College, Poondi, Tanjavur Dt. - 613 503, Tamil Nadu, India*Corresponding author.
M. N. Abubacker
PG and Research Dept of Botany, National College, Tiruchirappalli - 620 001, India.
Received on: 10-01-2010; Revised on: 19-03- 2010; Accepted on:08-02-2011-
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Author: M. N. Abubacker1 and S. Vasantha2
Title: Antibacterial activity of ethanolic leaf extract of Rauwolfia tetraphylla (Apocyanaceae) and its bioactive compound reserpine Journal: Drug Invention Today Vol(issue): 3 (March) Year: 2011 Page No: (16-17) -
Experimental Methods Keywords
Methodology: Antibacterial activity, Disc Diffusion Method, Inhibitory effect Research Materials: Rauwolfia tetraphylla
Keywords
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