Journal: Drug Invention Today

Article Id: JPRS-MSNS-0000891
Title: Antibacterial activity of ethanolic leaf extract of Rauwolfia tetraphylla (Apocyanaceae) and its bioactive compound reserpine
Category: Microbiological Study (on Natural/ Synthetic drug)
Section: Research Article
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  • Abstract

    In vitro antibacterial activity of ethanolic leaf extract of Rauwolfia tetraphylla was studied against selected pathogenic bacteria Bacillus cereus, Escherichia coli, Staphylococcus aureus and Yersinia enterocolitica by disc diffusion assay. Bioactive compound reserpine was isolated from the leaf. The results revealed that the ethanolic leaf extract and reserpine compound are potent in inhibiting these bacteria which cause gastroenteritis in human population. This work highlights that the inhibitory effect is on par with standard antibiotics.

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    Author(s) Name:

    M. N. Abubacker1 and S. Vasantha2

    Affiliation(s) Name:

    1PG and Research Dept of Botany, National College, Tiruchirappalli - 620 001, India.
    2PG and Research Dept of Botany, A.V.V.M. Sri Pushpam College, Poondi, Tanjavur Dt. - 613 503, Tamil Nadu, India

    *Corresponding author.
    M. N. Abubacker
    PG and Research Dept of Botany, National College, Tiruchirappalli - 620 001, India.


    Received on: 10-01-2010; Revised on: 19-03- 2010; Accepted on:08-02-2011

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    Author:

    M. N. Abubacker1 and S. Vasantha2

    Title:Antibacterial activity of ethanolic leaf extract of Rauwolfia tetraphylla (Apocyanaceae) and its bioactive compound reserpine
    Journal:Drug Invention Today
    Vol(issue):3 (March)
    Year:2011
    Page No: (16-17)
  • Experimental Methods Keywords

    Methodology:Antibacterial activity, Disc Diffusion Method, Inhibitory effect
    Research Materials:Rauwolfia tetraphylla

Keywords

Rauwolfia tetraphylla Reserpine Antibacterial activity Disc Diffusion Method Inhibitory effect

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