Journal: Journal of Pharmacy Research

Article Id: JPRS-PB-0000991
Title: Biological aspects of proteolytic enzymes: A Review
Category: Pharmaceutical Biotechnology
Section: Review Article
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    Protease plays an important role in the management of defense mechanism of living organisms. This review presents a comprehensive and exhaustive account of plant, animal and microbial enzymes with special reference to proteolytic properties. A large number of biological sources of proteases described in this review clearly demonstrate the importance of plants and microbial proteases in applied and industrial uses. Proteases have potential applications in food, dairy, detergent, leather, alcoholic beverages, brewing, meat, pharmaceutical and photographic industries. The research work on protease has been going on since seven decades but no exhaustive review on protease from last eleven years is available in the literature. This review attempts to focus on some of the difficulties observed in the earlier work and tried to find out possible solutions and bridging up this gap by introducing recent information regarding proteinases. This review provides information on diverse groups of proteases with respect to scientific name, family, purification scheme, protease inhibitors, physiological functions, also industrial applications, sequence homology and the future scope of protease enzymes.

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    Author(s) Name:

    Raghunath T. Mahajan and Shamkant B. Badgujar*

    Affiliation(s) Name:

    Department of Biotechnology, Moolji Jaitha College, Jalgaon: 425001, Maharashtra, India

    *Corresponding author.
    Shamkant Bhaskar Badgujar
    Department of Biotechnology,
    SSBT’s, College of Engineering and Technology,
    Bambhori, Post Box No-94, Jalgaon, Maharashtra, India

    Received on: 15-04-2010; Revised on: 20-06-2010; Accepted on:26-07-2010

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    Raghunath T. Mahajan and Shamkant B. Badgujar*

    Title:Biological aspects of proteolytic enzymes: A Review
    Journal:Journal of Pharmacy Research
    Vol(issue):3 (September)
    Page No: (2048-2068)
  • Experimental Methods Keywords

    Methodology:Biological aspects
    Research Materials:proteolytic enzymes


Endoprotease Exoprotease Protease structure Mode of action Protease inhibitor Sequence homology

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