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Journal of Pharmacy Research
ISSN NO: 0974-6943
The Journal of Pharmacy Research is an online Journal, publishing of correct version and document can be modified when, we/or author get comments from any readers. The journal is devoted to the promotion of Pharmaceutical sciences and related disciplines (including Pharmacy, medical, Biotech, Botany, organic and medicinal chemistry,  Nursing, Paramedical, prescription etc  fields).



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Journal: Journal of Pharmacy Research , Volume: 4, Issue: August
Article Id: JPRS-ND-00001357
Title: Canarium L. : A Phytochemical and Pharmacological Review
Category: Natural Drugs
Section: Review Article
Author Affiliation: 1School of Pharmacy, Faculty of Science, University of Nottingham(Malaysia Campus), Jln Broga, Semenyih, 43500, Selangor Darul Ehsan, Malaysia
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The genus Canarium L. consists of 75 species of aromatic trees which are found in the rainforests of tropical Asia, Africa and the Pacific. The medicinal uses, botany, chemical constituents and pharmacological activities are now reviewed. Various compounds are tabulated according to their classes their structures are given. Traditionally Canarium L. species have been used to treat a broad array of illnesses. Pharmacological actions for Canarium L. as discussed in this review include antimicrobial, antioxidant, anti-inflammatory, hepatoprotective and antitumor activity.

Journal: Journal of Pharmacy Research , Volume: 4, Issue: August
Article Id: JPRS-MB-00001378
Title: A comparative study of antimicrobial potential and phytochemical analysis of Artocarpus heterophyllus and Manilkara zapota seed extracts
Category: Microbiology
Section: Research Article
Author Affiliation: School of Biotechnology, Dr.G.R.Damodaran College of Science, Coimbatore-641014,Tamil Nadu, India
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The present study was undertaken to describe the comparative evaluation of phytochemical constituents and antimicrobial activity of Artocarpus heterophyllus and Manilkara zapota seeds in four different solvents. A preliminary phytochemical analysis was carried out and concluded that the presence of alkaloids, tannins, phenolic compounds, flavonoids and saponins in both extract. The antimicrobial activity was tested using agar well diffusion method against six bacterial and four fungal strains and whereas, gentamycin and chloramphenical as antibiotic standards. The results showed that the antibacterial and antifungal activities were effective in ethanol, acetone and aqueous fractions of seed extract than ethyl acetate fractions in both samples. The MIC was determined in four different solvents of both extracts and reported that ethanol, acetone and aqueous extract possess minimum inhibition in both extract than ethylacetate. From the present study, it can be concluded that Artocarpus heterophyllus and Manilkara zapota seed extracts has effective antimicrobial activity and potent phytochemical constituents.

Journal: Journal of Pharmacy Research , Volume: 4, Issue: August
Article Id: JPRS-QSAR-00002863
Title: QSAR Studies of Synthesized Quinazoline Derivatives
Category: QSAR Study
Section: Research Article
Author Affiliation: Department of Pharmaceutical Sciences, P.D.M.College of Pharmacy, Bahadurgarh, Haryana, INDIA-124507
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The purpose of this study was to develop Quantitative Structure Activity Relationship (QSAR) for selected Quinazoline derivatives. Multi-linear regression was used for data pruning and prediction of Activity and constructs the QSAR model from molecular descriptors that were generated using the TSAR, Codessa and Dragon computer programme. The final equation estimated with different descriptors. All show good significant correlation (r: 0.9-0.7). This investigation will help in rationalizing the design of new molecule and allow more rapid progression of potential drug candidates to the markets.