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Journal of Pharmacy Research
ISSN NO: 0974-6943
The Journal of Pharmacy Research is an online Journal, publishing of correct version and document can be modified when, we/or author get comments from any readers. The journal is devoted to the promotion of Pharmaceutical sciences and related disciplines (including Pharmacy, medical, Biotech, Botany, organic and medicinal chemistry,  Nursing, Paramedical, prescription etc  fields).



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Journal: Journal of Pharmacy Research , Volume: 5, Issue: June
Article Id: JPRS-P'Col-00005270
Title: Antidiabetic Activity of Aqueous Root Extract of Momordica cymbalaria Hook; on Streptozotocin Induced Wistar Rats
Category: Pharmacology
Section: Research Article
Author Affiliation: School of Life Sciences, S R T M University, Nanded, Maharashtra, India
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This study was designed to investigate the antidiabetic, hypoglycaemic properties of an aqueous root extract of Momordica cymbalaria H. the extract was obtained using soxhelation. After the oral administration of aqueous extract at a dose of 200 mg/kg and 500 mg/kg and glibenclamide (0.50 mg/kg) were administered for 15 days. A significant effect was observed at a dose of 500 mg/kg, which was comparable to the standard drug, glibenclamide. Both significantly decreases fasting blood glucose and increases the body weight in streptozotocin induced diabetic rats as compared to the animals in the diabetic control group. This investigation concludes Momordica cymbalaria H. aqueous root extract possess antidiabetic activity against Streptozotocin induced diabetic rats.