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Drug Invention Today
ISSN NO: 0975-7619
Drug Invention Today (DIT) was first published in 2009 by JPR Solutions. It is a journal, which publishes reviews, research papers and short communications . From 2019  Journal will be monthly twice ( vol 11& 12 with 2 Issues per month)
• Novel Drug Delivery Systems • Nanotechnology & Nanomedicine • Biotechnology related pharmaceutical technology • Polymeric bio-conjugates • Biological macromolecules • Biomaterials • Drug Information • Drug discovery/development • Screening of drugs from natural & synthetic origins • Novel therapeutic strategies • Combinatorial chemistry and parallel synthesis • Clinical trials • Case Reports
 Impact FactorTM ( India ) = 0.895 as on date (09.11.2018)
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Manuscripts Published

Journal: Drug Invention Today , Volume: 2, Issue: April
Article Id: JPRS-MSNS-0000932
Title: Antibacterial activity of aqueous plant extracts against Escherichia coli and Bacillus subtilis
Category: Microbiological Study (on Natural/ Synthetic drug)
Section: Research Article
Author Affiliation: Biotechnology,University Institute of Engineering and Technology,Kurukshetra University, Kurukshetra
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Spices are the key ingredients of the Indian food. Inspite of enhacing flavour of food, these are found to have medicinal importance too which is shown in our study. In this study, the antibacterial activity of aqueous leaf extracts of Mentha arvensis (Mint), Curcuma longa (Turmeric), Piper nigrum (Black pepper), Zingiber officinale (ginger) and Azadirachta indica (Neem) was evaluated against Escherichia coli and Bacillus subtilis by agar well diffusion method. The maximum antimicrobial activity expressed in terms of zone of inhibition was shown by aqueous extract of Zingiber officinale followed by Curcuma longa and Azadirachta indica. However, aqueous extract of Piper nigrum was only effective against B. subtilis and Mentha arvnesis did not show any activity against both the test organisms. This study scientifically validates the use of plants as a potent antibacterial agent.

Journal: Drug Invention Today , Volume: 2, Issue: April
Article Id: JPRS-MSNS-0000933
Title: Antimicrobial activity of Allium sativum ethanolic extract against food associated bacteria and fungi
Category: Microbiological Study (on Natural/ Synthetic drug)
Section: Research Article
Author Affiliation: Kurukshetra Institute of Technology and Management,Bhor Siadan, Kurukshetra-136119,Haryana, India
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The present study was designed to evaluate the in vitro antimicrobial activity of ethanolic extract of Allium sativum (garlic) against Gram-positive and Gram-negative food associated bacteria (Bacillus subtilis, B. megaterium, B. polymyxa, B. sphaericus, Staphylococcus aureus and Escherichia coli) and molds (Penicillium oxalicum, Aspergillus flavus, A. luchuensis, Rhizopus stolonifer, Scopulariopsis sp. and Mucor sp.) assayed by agar well diffusion method and poisoned food technique, respectively. The growth inhibition zone in garlic ethanolic extract against bacteria was in the range of 20mm to 31mm and in molds the percent mycelial growth inhibition  ranged between 20% and 50%. The garlic extract was not effective against P. oxalicum. The MIC values of garlic ethanolic extract for different bacterial and fungal isolates ranged from 10 mg/ml to 20mg/ml. The value of MBC and MFC equaled the MIC. Based on this finding, it may be suggested that these extracts may be used as natural antimicrobial additives to reclaim the shelf-life of foods.