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Drug Invention Today
ISSN NO: 0975-7619
Drug Invention Today (DIT) was first published in 2009 by JPR Solutions. It is a journal, which publishes reviews, research papers and short communications . From 2019  Journal will be monthly twice ( vol 11& 12 with 2 Issues per month)
• Novel Drug Delivery Systems • Nanotechnology & Nanomedicine • Biotechnology related pharmaceutical technology • Polymeric bio-conjugates • Biological macromolecules • Biomaterials • Drug Information • Drug discovery/development • Screening of drugs from natural & synthetic origins • Novel therapeutic strategies • Combinatorial chemistry and parallel synthesis • Clinical trials • Case Reports
 Impact FactorTM ( India ) = 0.895 as on date (09.11.2018)
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Manuscripts Published

Journal: Drug Invention Today , Volume: 4, Issue: September
Article Id: JPRS-PS-00001094
Title: Effect of electron beam radiations on memory in experimental animal models
Category: Pharmacological Screening
Section: Research Article
Author Affiliation: 1Department of Pharmacology, Nitte University, Mangalore, Karnataka, India-575018.
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Exposures to ionizing radiation have been an inevitable part of the environment. This type of radiation can disrupt atoms, creating positive and negative charged particles, and cause biological harm. Ionizing radiation includes x-rays, gamma rays, alpha particles, beta particles and neutrons. They have the potential to cause both beneficial and harmful effects. There are concerns about these radiations as they are widely used in hospitals for treatment and diagnosis of various diseases. The present work was designed to test the effect of whole body electron beam radiation on memory in mice using the Hebb Williams Maze, Elevated Plus Maze and Jumping apparatus, the commonly used exteroceptive models for cognitive tests in rodents. Mice were irradiated with three different doses (2Gy, 4Gy and 6Gy) of electron beam radiations. Statistical analysis revealed that whole body irradiation of the moderate dose range (2-6 Gy) of electron beam leads to a significant (p<0.001) loss of memory in irradiated mice. Electron beam induced memory loss can be due to radiation induced reactive oxygen species in brain.