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Drug Invention Today
ISSN NO: 0975-7619
Drug Invention Today (DIT) was first published in 2009 by JPR Solutions. It is a journal, which publishes reviews, research papers and short communications . From 2019  Journal will be monthly twice ( vol 11& 12 with 2 Issues per month)
• Novel Drug Delivery Systems • Nanotechnology & Nanomedicine • Biotechnology related pharmaceutical technology • Polymeric bio-conjugates • Biological macromolecules • Biomaterials • Drug Information • Drug discovery/development • Screening of drugs from natural & synthetic origins • Novel therapeutic strategies • Combinatorial chemistry and parallel synthesis • Clinical trials • Case Reports
 Impact FactorTM ( India ) = 0.895 as on date (09.11.2018)
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Manuscripts Published

Journal: Drug Invention Today , Volume: 4, Issue: January
Article Id: JPRS-CPS-0000892
Title: In Silico Screening of Drugs against Trypanosomes Using Blast
Category: Chemistry and Parallel Synthesis
Section: Editorial
Author Affiliation: St. Peter’s Engineering College, Chennai, Tamil Nadu, India.
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Human African Trypanosomiasis and Chagas Disease are diseases of poor people in Africa and Latin America respectively. The traditional market-driven pathways to drug development are not available. One potentially rapid and cost-effective approach to identifying and developing new trypanocidal drugs would be in silico screening of existing drugs already approved for other uses. Here BLAST is used for screening drugs against Trypanosomes. From the 1470 drugs analyzed, 121 passed the in silico test performed with the help of BLAST. Out of the 121 drugs, 61 drugs proved to be effective against Trypanosomes, 15 were confirmed to have no effect on Trypanosomes and the effectiveness of 45 drugs remained unknown. One result indicated that the enzyme phenylalanine-4-hydroxylase, which was previously unknown in Trypanosoma brucei, might be present in it. Hence BLAST is a tool which can be used for in silico screening of existing drugs is a rapid, cheap and effective way.

Journal: Drug Invention Today , Volume: 4, Issue: January
Article Id: JPRS-CA-0000893
Title: Phytochemical and Pharmacognostical Studies on Murraya koenigii (L)spreng. Roots
Category: Compounds ( Natual and Synthetic ) Analysis
Section: Editorial
Author Affiliation: Chitkara College of Pharmacy, Chitkara University, Chandigarh-Patiala NH-64, Rajpura, Patiala-140401, Punjab, India
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The Murraya koenigii plant is widely used as herb, spice, condiments and also used to treat various types of ailments in Indian traditional system. Worlds about 80% population relies upon herbal products, because they have been considered as safe, effective and economical. The present study was aimed to set standard parameters for standardization of Murraya koenigii roots. In the present study microscopy of root and roots powder carried out, ash values, extractive values, fiber content, bitterness value, haemolytic activity, tannin content and roots powder fluorescence nature also observed using different chemical reagents. The alcoholic and aqueous extracts were screened for presence of amino acid and carbohydrates. The preliminary phytochemical screening of petroleum ether extract, ethyl acetate extract, chloroform extract, ethanol extract and aqueous extract was performed. The presence of alkaloids, flavonoids, carbohydrates, and sterol in various extracts were observed. This is first ever pharmacognostical study carried out on Murraya koenigii roots.