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Drug Invention Today
ISSN NO: 0975-7619
Drug Invention Today (DIT) was first published in 2009 by JPR Solutions. It is a journal, which publishes reviews, research papers and short communications . From 2019  Journal will be monthly twice ( vol 11& 12 with 2 Issues per month)
• Novel Drug Delivery Systems • Nanotechnology & Nanomedicine • Biotechnology related pharmaceutical technology • Polymeric bio-conjugates • Biological macromolecules • Biomaterials • Drug Information • Drug discovery/development • Screening of drugs from natural & synthetic origins • Novel therapeutic strategies • Combinatorial chemistry and parallel synthesis • Clinical trials • Case Reports
 Impact FactorTM ( India ) = 0.895 as on date (09.11.2018)
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Manuscripts Published

Journal: Drug Invention Today , Volume: 9, Issue: May
Article Id: JPRS-PS-00001727
Title: Hepatoprotective activity of Bridelia retusa leaves against paracetamol-induced liver damage in Swiss albino mice
Category: Pharmacological Screening
Section: Research Article
Author Affiliation: Department of Pharmaceutical Sciences, Bhagwant University, Ajmer, Rajasthan.India.
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The present study is aimed to evaluating the hepatoprotective effect of Bridelia retusa leaves extracts by paracetamol-induced liver damage in swiss albino mice.The degree of protection was measured by using biochemical parameters such as serum glutamate oxalate transaminase (SGOT), serum glutamate pyruvate transaminase (SGPT), alkaline phosphatase (ALP), bilirubin.. Treatment with Bridelia retusa leaves extracts showed significant reduction in level of SGOT, SGPT, ALP and total bilirubin almost comparable to the Silymarin. The hepatoprotection confirmed by histopathological examination of the liver tissue. From the result it can be concluded that Bridelia retusa leaves possesses hepatoprotective effect against paracetamol –induced liver damage in mice.

Journal: Drug Invention Today , Volume: 9, Issue: May
Article Id: JPRS-CPS-00001779
Title: Synthesis, characterization and antimicrobial activity of metal complexes derived from nitro aniline and 3-aldehydosalicylic acid
Category: Chemistry and Parallel Synthesis
Section: Research Article
Author Affiliation: Research and Development centre, Bharathiar University, Coimbatore and Department of Chemistry, BGMIT, Mudhol, District Bagalakoti, State Karnataka,India.
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 Objective: The aim of the present work was to synthesize different types of complex compounds of three Schiff base ligands with metal ions. Methods: New Schiff base ligands formed by the condensation of 3-Aldehydosalicylic acid with equimolar quantity of para, meta and ortho nitro aniline. The complexes of metal ions like Cu (II), Zn (II), Ni (II), Co (II)  with Schiff base ligands (ML2) have been synthesized at pH range7 . All the synthesized Schiff bases and metal complexes were characterized by elemental analysis, FTIR, 1HNMR and mass spectral data. Results: Study reveals that the Schiff base ligands involved the donor COOH, OH and Nitrogen atom. The ligands ML2 in metal complexes behave as dibasic tridentate OON at pH range7. Spectral analysis indicates square pyramidal geometries for all the complexes.  The Schiff bases and metal complexes were screened for their antifungal and antibacterial activities. Conclusion: The Cu (II) and Zn (II) complexes exhibited good antimicrobial activity when compared to the free ligand.