Journal Menu

Issues

Journal of Pharmacy Research
ISSN NO: 0974-6943
The Journal of Pharmacy Research is an online Journal, publishing of correct version and document can be modified when, we/or author get comments from any readers. The journal is devoted to the promotion of Pharmaceutical sciences and related disciplines (including Pharmacy, medical, Biotech, Botany, organic and medicinal chemistry,  Nursing, Paramedical, prescription etc  fields).



Following Indexing in form of Journal name, link, full text , Abstract or pdf collector or Aggregator.

      Recent Manuscripts published

      Journal: Journal of Pharmacy Research

      Title: Study on the incidence and prevalence of oral manifestations in anemic patients
      Section: Review Article
      Category: Pharmacology
      Country: India
      View Article

      The main aim of this study is to find the clinical manifestations in varied hemoglobin (Hb) level in anemia and to find the varied oral manifestations in patients with anemia. Decrease in the Hb concentration of the blood below the normal range (normal Hb levels: male - 13.5–17g/dl; female - 12–15g/dl) is known as anemia, and thereby, this study is conducted on people with pre-existing anemia. The various oral manifestations in anemic patients were examined to establish the influence and relationship between the decrease of Hb value and the different oral manifestations.

      Journal: Journal of Pharmacy Research

      Title: Development and validation of a sensitive RP-HPLC method for quantitative determination of imatinib mesylate in complex dosage forms like drug eluting coronary stents
      Section: Research Article
      Category: Pharmaceutics
      Country: India
      View Article

      Aim: The present study is aimed to develop and validate an accurate, precise, and simple reversed-phase–high-performance liquid chromatography (HPLC) method for the estimation of imatinib mesylate (IM) released from the IM-coated stents. Materials and Methods: Different chromatographic conditions were tried for IM separation in the placebo (uncoated stents) and validated as per ICH guidelines. The validated HPLC method is applied to measure IM released from IM-coated stents. Results: The chromatographic separation was achieved on C18 column (250 mm × 4.6 mm i.e., 5 μm) with a mobile phase consisting of methanol-water-glacial acetic acid (65:35:0.03%, v/v) at a flow rate of 1.0 ml/min. Detection was carried out at 267 nm with photodiode array detector and IM eluted at 5.02 min (retention time) with no interfering peak of excipients used for the preparation of dosage form. The method was linear over the range from 0.3 to 9 μg/mL (R2 = 0.999). The intraday and interday precision values were <2%. Limit of detection and limit of quantitation were 0.2 μg/mL and 0.5 μg/mL, respectively. Conclusion: The method validated according to ICH guidelines and successfully applied for quantitative analysis and release studies of complex pharmaceutical dosage form like IM-coated stent.

      Journal: Journal of Pharmacy Research

      Title: Preparation and characterization of lacidipine as an oral fast dissolving film
      Section: Research Article
      Category: Pharmaceutics
      Country: India
      View Article

      Background: Fast dissolving oral drug delivery system is solid dosage form which disintegrates or dissolves within second when placed in the mouth without need of water or chewing. In present investigation, an attempt has been made to develop oral fast dissolving film of calcium channel blocker lacidipine. Method: Five formulas were prepared by solvent casting method using HPMC (METOLOSE) ® as a film forming polymer and evaluated for their physical characteristics such as thickness, weight variation, folding endurance, drug content, disintegration time and in vitro drug release. The compatibility of the drug in the formulation was confirmed by FTIR and DSC studies. Result and Conclusion: The optimized formula F1 showed minimum in vitro disintegration time of 25 second and highest dissolution rate 97.3% in 10 minutes with good mechanical properties. Based on overall results, the conclusion that lacidipine was successfully prepared as oral fast dissolving film with accepted properties.